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KMID : 0974620000180020067
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Bulletin of Dongnam Health University
2000 Volume.18 No. 2 p.67 ~ p.73
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Formation and Secreting Mechanism of Mucin in Gastric Mucus Cell
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Abstract
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Mucin formation and secreting mechanism in mucous cell of stomach were described using transmission electron microscopy. Mucous cells produce mucin granules whose main function is to protect the lining of the stomach. Activated gastric mucous cells have a centrally located nucleus which shaped spindle form. The cytoplasm of these cell have well developed rough endoplasmic reticulum and Golgi complex. The dilated cisternae of rough endoplasmic reticulum was prominant in these cell specialized for protein secretion such as mucin granules. The mucin granule were synthesized on the rough endoplasmic reticulum adjacent nucleus and formed sperical shape of 1.3mm in diameter. The cytoplasm of mucous cells accumulated of mucin granules. These limiting membrane of mucin granules fuse near the cell membrane, condensed mucin grnaules that migrate laterally and secreted to the lumen.
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